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However, testosterone in physiologic doses might even be helpful in sufferers with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood flow in males with established coronary artery illness . Therefore, an interaction of endogenous elements of the patient’s threat profile as properly as the testosterone dosing may be issues of whether or not adverse events occur. Erythrocytosis has been reported as a potential effect of testosterone, which can be useful in patients with anemia. The greatest danger of erythrocytosis happens with injectable forms of testosterone compared with transdermal preparations, particularly in supraphysiologic doses. An enhance of up to 44% of the baseline hematocrit has been reported .
- Other widespread potential antagonistic effects include infertility, hepatotoxicity, psychological abnormalities, and gynecomastia .
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- Patients commonly develop left ventricular hypertrophy, which can be related to hypertension, one other antagonistic impact of AAS.
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